ECC Expertise / About us
Maintaining Excellent Customer Relationships
ECC (Estermann Chemical Consulting) founder and president, Dr. Heinrich Estermann, holds a doctorate in preparative organic chemistry from ETH Zurich (Switzerland) which he obtained under Prof. Dr. D. Seebach with a thesis on stereoselective synthesis. After spending a post-doctorate at Sandoz East Hanover NJ, USA in the chemical development department, he held the position of plant manager in chemical development at Roche for 20 years. In addition, he managed technical projects outsourced to CDMOs for more than 10 years. The profound professional knowledge and experience he acquired throughout his career includes (but is not limited to):
Scale-up
Development production
Commercial production
Safety in the chemical industry (safety investigations, reaction calorimetry, process risk assessment (HAZOP/hazard and operability study)
GMP including quality risk assessment
Process validation (laboratory and plant)
Environment protection including regulations (e.g. REACH)
Special technologies at the plant (1000 und 2500 l reactors)
Reactions involving high pressure (up to 100 bar, with hydrogen, carbon monoxide, ammonia, etc.)
- Cryo reactions (up to -100 °C), reactions with n-BuLi, s-BuLi, etc.
- Catalytical enantioselective reactions
- Chromatography (up to 45 cm columns, all stationary phases, chiral included)
- Continuous distillation (whiped thin film, short path)
- Rectification
- Continuous extraction (centrifugal extractors, counter current extractors)